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Comparison of Type 1 & 2 Diabetes on a Pediatric Population and the Risk of Developing Retinopathy

Article Name: Ocular Sequelae in a Population-Based Cohort of Youth Diagnosed With Diabetes During a 50-Year Period

Article Summary:

The goal of this study was to assess the risk of diabetic children developing diabetic retinopathy over a 50-year period. Medical records from all residents of Olmsted County, Minnesota were consulted from January 1, 1970, through December 31, 2019. The population studied included all patients with diabetes younger than 22 years. 606 patients were included in the study with a diagnosis of type 1 or 2 diabetes. 525 children of the 606 underwent an eye examination and therefore 81 were excluded from the study. The ocular pathologies analyzed by the authors consisted of visually significant cataract, diabetic macular edema, nonproliferative and proliferative diabetic retinopathy, and the treatment of pars plana vitrectomy.

17 of the 64 patients (26.6%) with type 2 diabetes and 147 of the 461 patients (31.9%) with type 1 diabetes were found to have retinopathy due to the diabetes. The evaluation of the risk for developing any diabetic retinopathy between type 2 and type 1 diabetes patients was found to be 1.88 (95%CI, 1.13-3.12; P = .02). Additionally, the timeline in which patients with type 2 diabetes developed retinopathy was shorter than the patients with type 1 diabetes. Patients suffering from type 2 diabetes had more chances to undergo pars plana vitrectomy by 15 years after their diabetes diagnosis 4.06 (95%CI, 1.34-12.33; P = .007). The authors are hoping this study illustrates the importance of ophthalmic monitoring of patients with type 2 diabetes.

Publication date: July 2022

Author: Maya Alik


Bai P, Barkmeier AJ, Hodge DO, Mohney BG. Ocular Sequelae in a Population-Based Cohort of Youth Diagnosed With Diabetes During a 50-Year Period. JAMA Ophthalmol. 2022;140(1):51-57. doi:10.1001/jamaophthalmol.2021.5052


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